"Recreational use of Ergoline Alkaloids from Argyreia Nervosa" William E. Shawcross Journal of Psychedelic Drugs Vol. 15(4) Oct-Dec 1983 CHEMISTRY AND EFFECT OF THE SEEDS The Hawaiian baby woodrose entered the drug scene in 1965 with the publication of a paper in "Science" entitled "Ergoline Alkaloids in Tropical Wood Roses" by Hylin and Watson. The wide circulation of this journal assured thorough dissemination of the information they presented. They wrote, "The possible health and legal problems associated with the presence of similar compounds in commerically cultivated plants led us to examine the ornamental wood roses, Ipomoea tuberosa and Argyreia nervosa, both common Hawaiian crops that have assumed commerical importance as components of [the] dried tropical flower industry." Comparing the seeds of these two plants with those of the morning glory varieties Pearly Gates and Heavenly Blue, they found the following yield of alkaloids (mg of alkaloid/g of seed material): Heavenly Blue 0.813 Pearly Gates 0.423 I. tuberosa [None] A. nervosa 3.050 The seed of A. nervosa is the best plant source of ergoline alkaloids discovered; it contains approximately 3 mg of alkaloidal material per gram of seed. Approximately one-eighth of this is lysergamide. Hylin and Watson found the major alkaloidal constituents in A. nervosa seeds to be ergine (780 mcg/g of fresh seed) and isoergine and penniclavine (555 mcg). [Note: Argyreia nervosa has NO history of shamanic use as a hallucinogen]